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Regulation of the Clara Cell Secretory Protein/Uteroglobin Promoter in Lung

1 Dec 2000

Abstract excerpt

Clara cell secretory protein/uteroglobin (CCSP/UG) is specifically expressed in the conducting airway epithelium of the lung in a differentiation-dependent manner. The proximal promoter region of the rodent CCSP/UG gene directs Clara cell specificity. Previously, it was shown that the forkhead transcription factors HNF-3 alpha and beta and the homeodomain factor TTF-1 are important transcription factors acting...

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PMID: 11193754
DOI: 10.1111/j.1749-6632.2000.tb05527.x

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