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Article

PARP-1 Val762Ala polymorphism, CagA+ H. pylori infection and risk for gastric cancer in Han Chinese population.

Molecular biology reports - 1 Jul 2009

Zhang Quanbao, Li Yumin, Li Xun, Zhou Wence, Shi Bin, Chen Hao, Yuan Wenzhen

Abstract excerpt

INTRODUCTION: PARP-1 plays important role in the BER (base excision repair) and maintenance of genomic integrity. Previous study found the Val762Ala genetic variant in the PARP-1 gene contributed to susceptibility of some cancers and decreased PARP-1 enzyme activity in response to oxidative damage. Helicobacter pylori (H. pylori) infection was thought to be one of the major causes of gastric cancer. In this...

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PMID: 18716896
DOI: 10.1007/s11033-008-9336-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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