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DNA Damage Repair and Current Therapeutic Approaches in Gastric Cancer: A Comprehensive Review

12 Aug 2022

Abstract excerpt

DNA in cells is frequently damaged by endogenous and exogenous agents. However, comprehensive mechanisms to combat and repair DNA damage have evolved to ensure genomic stability and integrity. Improper DNA damage repair may result in various diseases, including some types of tumors and autoimmune diseases. Therefore, DNA damage repair mechanisms have been proposed as novel antitumor drug targets. To date,...

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Identifiers

PMID: 36035159
DOI: 10.3389/fgene.2022.931866

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