Article
PARP-1 Val762Ala polymorphism is associated with risk of cervical carcinoma.
PloS one - 1 Jan 2012
Ye Feng, Cheng Qi, Hu Yuting, Zhang Jing, Chen Huaizeng
Abstract excerpt
PARP-1 is a nuclear enzyme that plays an important role in DNA repair, recombination, proliferation and the genome stability. The PARP-1 Val762Ala polymorphism has been associated with increased risk of developing cancers of the prostate, esophagus and lung. The aim of this study was to determine whether the PARP-1 Val762Ala polymorphism is associated with the risk of cervical carcinoma. MA-PCR was used to...
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