Article
The 3'UTR NFKBIA variant is associated with extensive colitis in Hungarian IBD patients.
Digestive diseases and sciences - 1 Feb 2009
Szamosi Tamas, Lakatos Peter Laszlo, Szilvasi Aniko, Lakatos Laszlo, Kovacs Agota, Molnar Tamas, Altorjay Istvan, Papp Maria, Szabo Orsolya, Satori Anna, Tulassay Zsolt, Miheller Pal, Horvath Henrik Csaba, Papp Janos, Tordai Attila, Andrikovics Hajnalka
Abstract excerpt
PURPOSE: In previous studies the NFKBIA 3'UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/delATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or disease phenotype in Hungarian inflammatory bowel disease (IBD) patients. METHODS: NFKBIA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
