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Article

Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes.

Inflammatory bowel diseases - 1 Jul 2006

Glas Jürgen, Török Helga-Paula, Tonenchi Laurian, Müller-Myhsok Bertram, Mussack Thomas, Wetzke Martin, Klein Wolfram, Epplen Joerg T, Griga Thomas, Schiemann Uwe, Lohse Peter, Seiderer Julia, Schnitzler Fabian, Brand Stephan, Ochsenkühn Thomas, Folwaczny Matthias, Folwaczny Christian

Abstract excerpt

BACKGROUND: Recently, an association of the NFKB1 polymorphism -94ins/delATTG with ulcerative colitis (UC) has been reported. This 4-bp insertion/deletion polymorphism is localized in the promoter region of the NFKB1 gene and appears to be functionally relevant. The aim of the present study was t...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Inflammatory Bowel Diseases

Share to Interleukin 1 Receptor Antagonist Protein

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 16804398
DOI: 10.1097/01.ibd.0000225346.23765.6b

Genes

NFKB1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16804398-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes.PMID 16804398Read ↗

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A functional polymorphism of the NFKB1 promoter is not associated with ulcerative colitis in a Spanish population.Semantic proximity Read ↗

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