Article
NADPH oxidase p22phox polymorphisms and oxidative stress in patients with obstructive sleep apnoea.
Respiratory medicine - 1 Nov 2011
Piérola Javier, Alemany Alexandra, Yañez Aina, de-la-Peña Mónica, Sánchez-de-la-Torre Manuel, Esquinas Cristina, Pérez-Gutierrez Camino, Burguera Bartolomé, Barbé Ferran, Barceló Antonia
Abstract excerpt
BACKGROUND: Obstructive Sleep Apnoea (OSA) is associated with increased oxidative stress. NADPH oxidases are the main source of Reactive Oxygen Species (ROS) in the vasculature. Several polymorphisms related to NADPH oxidase expression or activity have been identified. We compared the distribution of the allelic frequencies of A-930G and C242T polymorphisms and their possible relationship with the levels of...
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