Article
The phenotypic spectrum related to the human epilepsy susceptibility gene "EJM1".
Annals of neurology - 1 Aug 1995
Sander T, Hildmann T, Janz D, Wienker T F, Neitzel H, Bianchi A, Bauer G, Sailer U, Berek K, Schmitz B
Abstract excerpt
Linkage studies of families ascertained through patients with juvenile myoclonic epilepsy (JME) suggest that an HLA-linked susceptibility gene on chromosome 6, designated "EJM1," predisposes to a group of idiopathic generalized epilepsies (IGEs) comprising JME, juvenile absence epilepsy (JAE), ch...
Topics
- Disease Susceptibility
- Epilepsy
- Female
- Genetic Linkage
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Male
- Pedigree
- Phenotype