Article

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

2020-02-20

Abstract excerpt

Staphylococcus aureus infects approximately 30% of the human population and causes a spectrum of pathologies ranging from mild skin infections to life-threatening invasive diseases. The strict host specificity of its virulence factors has severely limited the accuracy of in vivo models for the development of vaccines and therapeutics. To resolve this, we generated a humanised zebrafish model and determined that n...

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Identifiers and source

Literature Corpus work: 9de08140-6ecc-5e7c-b440-a5e70dd4c884
DOI: 10.1101/2020.02.18.955021

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