Article
Distilling artificial recombinants from large sets of complete mtDNA genomes.
PloS one - 20 Aug 2008
Kong Qing-Peng, Salas Antonio, Sun Chang, Fuku Noriyuki, Tanaka Masashi, Zhong Li, Wang Cheng-Ye, Yao Yong-Gang, Bandelt Hans-Jürgen
Abstract excerpt
BACKGROUND: Large-scale genome sequencing poses enormous problems to the logistics of laboratory work and data handling. When numerous fragments of different genomes are PCR amplified and sequenced in a laboratory, there is a high imminent risk of sample confusion. For genetic markers, such as mitochondrial DNA (mtDNA), which are free of natural recombination, single instances of sample mix-up involving different...
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