Article
An accurate method for identifying recent recombinants from unaligned sequences.
Bioinformatics (Oxford, England) - 28 Mar 2022
Feng Qian, Tiedje Kathryn E, Ruybal-Pesántez Shazia, Tonkin-Hill Gerry, Duffy Michael F, Day Karen P, Shim Heejung, Chan Yao-Ban
Abstract excerpt
MOTIVATION: Recombination is a fundamental process in molecular evolution, and the identification of recombinant sequences is thus of major interest. However, current methods for detecting recombinants are primarily designed for aligned sequences. Thus, they struggle with analyses of highly diverse genes, such as the var genes of the malaria parasite Plasmodium falciparum, which are known to diversify primarily...
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