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Article

A network approach to analyzing highly recombinant malaria parasite genes.

PLoS computational biology - 1 Jan 2013

Larremore Daniel B, Clauset Aaron, Buckee Caroline O

Abstract excerpt

The var genes of the human malaria parasite Plasmodium falciparum present a challenge to population geneticists due to their extreme diversity, which is generated by high rates of recombination. These genes encode a primary antigen protein called PfEMP1, which is expressed on the surface of infected red blood cells and elicits protective immune responses. Var gene sequences are characterized by pronounced...

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Identifiers

PMID: 24130474
DOI: 10.1371/journal.pcbi.1003268
PMCID: PMC3794903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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