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No evidence for intermolecular recombination in human fibroblast and blood mtDNA from individuals with biparental mtDNA transmission

2020-02-26

Abstract excerpt

Strictly maternal inheritance and lack of intermolecular recombination of the human mitochondrial genome (mtDNA) are the assumed preconditions for molecular evolution studies, phylogenetic reconstruction and population genetic analyses. This hypothesis, however, has been challenged by investigations providing evidence for genetic recombination of mtDNA, thus sparking controversy. Using single-molecule real-time (S...

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Literature Corpus work
7b0481ec-a066-5dc2-b106-1509a40684f4
DOI
10.1101/2020.02.26.941922
Open publication

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No evidence for intermolecular recombination in human fibroblast and blood mtDNA from individuals with biparental mtDNA transmissionDOI 10.1101/2020.02.26.941922
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