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Article

Rare creation of recombinant mtDNA haplotypes in mammalian tissues.

Proceedings of the National Academy of Sciences of the United States of America - 26 Apr 2005

Sato Akitsugu, Nakada Kazuto, Akimoto Miho, Ishikawa Kaori, Ono Tomoko, Shitara Hiroshi, Yonekawa Hiromichi, Hayashi Jun-Ichi

Abstract excerpt

The problem of whether recombinant mtDNAs are created in mammalian cells has been controversial for many years. We show convincing evidence for the very rare creation of recombinant mtDNA haplotypes by isolating human somatic hybrid cells and by generating mice carrying two different mtDNA haplot...

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Share to Cell Line
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Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Ribosomal

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Source

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Identifiers

PMID: 15829586
DOI: 10.1073/pnas.0408666102
PMCID: PMC1087914

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15829586-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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