Article
The vesicular integral protein-like gene is essential for development of a mechanosensory system in zebrafish.
Developmental neurobiology - 1 Oct 2008
Chong Mabel, Liao Meijiang, Drapeau Pierre
Abstract excerpt
The zebrafish hi472 mutation is caused by a retroviral insertion into the vesicular integral protein-like gene, or zVIPL, a poorly studied lectin implicated in endoplasmic reticulum (ER)-Golgi trafficking. A mutation in the shorter isoform of zVIPL (zVIPL-s) results in a reduction of mechanosensitivity and consequent loss of escape behavior. Here we show that motoneurons and hindbrain reticulospinal neurons,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.