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Article

Ethnic benign neutropenia: A phenomenon finds an explanation.

Pediatric blood & cancer - 1 Dec 2018

Palmblad Jan, Höglund Petter

Abstract excerpt

Ethnic benign neutropenia (ENP) is the most common form of neutropenia (NP) worldwide, if an absolute blood neutrophil count (ANC) of < 1.5 G/L is used as definition. In 2009, ENP was associated with a gene variation in the ACKR1/DARC gene, the same variation that also confers the Duffy-null trait. In 2017, a novel mechanism for ENP was introduced, questioning if ENP is a true neutropenic state, when the body's...

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Identifiers

PMID: 30117263
DOI: 10.1002/pbc.27361

Genes

ACKR1

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