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Interleukin-18 promoter polymorphisms and risk of late onset Alzheimer's disease.

Brain research - 9 Feb 2009

Yu Jin-Tai, Tan Lan, Song Jing-Hui, Sun Yan-Ping, Chen Wei, Miao Dan, Tian Yan

Abstract excerpt

Pro- and anti-inflammatory cytokines play an important role in Alzheimer's disease (AD), and common polymorphisms of genes controlling their production have been shown to be associated with the susceptibility to sporadic AD. Interleukin (IL)-18 is a potent pro-inflammatory cytokine of the IL-1 superfamily, and increasing evidences indicate a crucial role for it in the pathogenesis of AD. To clarify the role of...

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Identifiers

PMID: 19073159
DOI: 10.1016/j.brainres.2008.11.083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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