Article
Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population.
BMC medical genomics - 27 Jun 2021
Cui Jiaqi, Tong Rui, Xu Jing, Tian Yanni, Pan Juan, Wang Ning, Chen Huan, Peng Yanqi, Fei Sijia, Ling Wang, Guo Chaoying, Yao Juanchuan, Cui Wei
Abstract excerpt
BACKGROUND: Evidence from genetic epidemiology indicates that type 2 diabetes (T2D) has a strong genetic basis. Activated STAT4 has an inflammatory effect, and STAT4 is an important mediator of inflammation in diabetes. Our study aimed to study the association between STAT4 single nucleotide polymorphisms (SNPs) and T2D susceptibility in Chinese Han population. METHODS: We conducted a 'case-control' study among...
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