Article
Loss of asymmetry in D2 receptors of putamen in unaffected family members at increased genetic risk for schizophrenia.
Acta psychiatrica Scandinavica - 1 Sept 2008
Lee K J, Lee J S, Kim S J, Correll C U, Wee H, Yoo S Y, Jeong J M, Lee D S, Lee S I, Kwon J S
Abstract excerpt
OBJECTIVE: Dopamine dysregulation has been implicated in the pathophysiology of schizophrenia. The present study was performed to examine whether unaffected relatives at high genetic risk of schizophrenia have dopamine dysregulation in comparison with healthy controls. METHOD: Eleven unaffected relatives from families with two or more first- or second-degree relatives with schizophrenia (n = 9) or with a...
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