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Article

Abnormal relationship between medial temporal lobe and subcortical dopamine function in people with an ultra high risk for psychosis.

Schizophrenia bulletin - 1 Sept 2012

Allen Paul, Chaddock Christopher A, Howes Oliver D, Egerton Alice, Seal Marc L, Fusar-Poli Paolo, Valli Isabel, Day Fern, McGuire Philip K

Abstract excerpt

BACKGROUND: Neuroimaging studies in humans have implicated both dysfunction of the medial temporal lobe (MTL) and the dopamine system in psychosis, but the relationship between them is unclear. We addressed this issue by measuring MTL activation and striatal dopaminergic function in individuals with an At Risk Mental State (ARMS) for psychosis, using functional magnetic resonance imaging (fMRI) and positron...

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Identifiers

PMID: 21536784
DOI: 10.1093/schbul/sbr017
PMCID: PMC3446221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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