Article
Basal ganglia shape abnormalities in the unaffected siblings of schizophrenia patients.
Biological psychiatry - 15 Jul 2008
Mamah Daniel, Harms Michael P, Wang Lei, Barch Deanna, Thompson Paul, Kim Jaeyun, Miller Michael I, Csernansky John G
Abstract excerpt
BACKGROUND: Abnormalities of basal ganglia structure in schizophrenia have been attributed to the effects of antipsychotic drugs. Our aim was to test the hypothesis that abnormalities of basal ganglia structure are intrinsic features of schizophrenia by assessing basal ganglia volume and shape in the unaffected siblings of schizophrenia subjects. METHOD: The study involved 25 pairs of schizophrenia subjects and...
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