Article
Genetic epidemiology of osteoarthritis: recent developments and future directions.
Current opinion in rheumatology - 1 Mar 2013
Hochberg Marc C, Yerges-Armstrong Laura, Yau Michelle, Mitchell Braxton D
Abstract excerpt
PURPOSE OF REVIEW: Despite the high prevalence of osteoarthritis and its enormous public health impact, the cause of the disease remains largely obscure. The identification of genes associated with osteoarthritis can help reveal underlying biological mechanisms that may lead to development of new therapeutic targets or biomarkers for early detection and risk stratification. The goal of this short review is to...
Topics
- Arthralgia
- Body Mass Index
- Bone Density
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Osteoarthritis
- Phenotype
- Polymorphism, Single Nucleotide
- Risk Factors
