Article
Genetic variants in GTF2H1 and risk of lung cancer: a case-control analysis in a Chinese population.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2009
Wu Wenting, Liu Hongliang, Lei Rong, Chen Dan, Zhang Shuyu, Lv Juan, Wang Yi, Fan Weiwei, Qian Ji, Jin Guangfu, Ma Hongxia, Miao Ruifen, Hu Zhibin, Wang Haifeng, Jin Li, Wei Qingyi, Shen Hongbing, Huang Wei, Lu Daru
Abstract excerpt
GTF2H1, the p62 subunit of the multiprotein complex transcription factor IIH (TFIIH), participates in both the nucleotide excision repair process and transcription control by specifically interacting with a variety of factors important in carcinogenesis. To elucidate the role of genetic variation in GTF2H1 in the etiology of lung cancer, we conducted a case-control study of 500 incident lung cancer cases and 517...
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