Article
MTF1 genetic variants are associated with lung cancer risk in the Chinese Han population.
BMC cancer - 28 Jun 2024
Cheng Yujing, Zhang Chan, Li Qi, Yang Xin, Chen Wanlu, He KunHua, Chen Mingwei
Abstract excerpt
BACKGROUND: Metal-regulatory transcription factor 1 (MTF1), a conserved metal-binding transcription factor in eukaryotes, regulates the proliferation of cancer cells by activating downstream target genes and then participates in the formation and progression of tumors, including lung cancer (LC). The expression level of MTF1 is down-regulated in LC, and high expression of MTF1 is associated with a good prognosis...
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