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Article

Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe.

Molecular and cellular biology - 1 Dec 1992

Speiser D M, Ortiz D F, Kreppel L, Scheel G, McDonald G, Ow D W

Abstract excerpt

Phytochelatins (PCs) are metal-chelating peptides produced in plants and some fungi in response to heavy metal exposure. A Cd-sensitive mutant of the fission yeast Schizosaccharomyces pombe, defective in production of a PC-Cd-sulfide complex essential for metal tolerance, was found to harbor mutations in specific genes of the purine biosynthetic pathway. Genetic analysis of the link between metal complex...

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Identifiers

PMID: 1448066
DOI: 10.1128/mcb.12.12.5301-5310.1992
PMCID: PMC360467

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Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe.PMID 1448066Read ↗

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