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Article

Insulation of the ubiquitous Rxrb promoter from the cartilage-specific adjacent gene, Col11a2.

The Journal of biological chemistry - 10 Oct 2008

Murai Junko, Ikegami Daisuke, Okamoto Mina, Yoshikawa Hideki, Tsumaki Noriyuki

Abstract excerpt

The retinoid X receptor beta gene (Rxrb) is located just upstream of the alpha2(XI) collagen chain gene (Col11a2) in a head-to-tail manner. However, the domain structures of these genes are unknown. Col11a2 is specifically expressed in cartilage. In the present study, we found Rxrb expression in various tissues with low expression in the cartilage. Col11a2 1st intron enhancer directed cartilage specific...

Read the complete abstract on PubMed

Topics

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Share to Cartilage
Share to Chromosomes, Artificial, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Collagen Type XI

Share to Enhancer Elements, Genetic

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Share to Mice, Transgenic

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Source

Identifiers

PMID: 18682388
DOI: 10.1074/jbc.M803657200

Genes

RXRB
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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