Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a repressor in the first intron of the human alpha2(I) collagen gene (COL1A2).

The Journal of biological chemistry - 21 Oct 2005

Antoniv Taras T, Tanaka Shizuko, Sudan Bayan, De Val Sarah, Liu Ke, Wang Lu, Wells Dominic J, Bou-Gharios George, Ramirez Francesco

Abstract excerpt

The human and mouse genes that code for the alpha2 chain of collagen I (COL1A2 and Col1a2, respectively) share a common chromatin structure and nearly identical proximal promoter and far upstream enhancer sequences. Despite these homologies, species-specific differences have been reported regarding the function of individual cis-acting elements, such as the first intron sequence. In the present study, we have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Collagen Type I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Deoxyribonuclease I

Share to GATA4 Transcription Factor

Share to Interferon Regulatory Factor-1

Share to Interferon Regulatory Factors

Share to Mice, Inbred CBA

Share to NIH 3T3 Cells

Source

Identifiers

PMID: 16091368
DOI: 10.1074/jbc.M502681200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a repressor in the first intron of the human alpha2(I) collagen gene (COL1A2).PMID 16091368Read ↗

Characterization of an Evolutionarily Conserved Far-upstream Enhancer in the Human α2(I) Collagen (COL1A2) GeneSemantic proximity Read ↗

Different cis-Regulatory DNA Elements Mediate Developmental Stage- and Tissue-specific Expression of the Human COL2A1 Gene in Transgenic MiceSemantic proximity Read ↗

Chondrocyte-specific Enhancer Elements in the Col11a2 Gene Resemble the Col2a1 Tissue-specific EnhancerSemantic proximity Read ↗

Two different negative and one positive regulatory factors interact with a short promoter segment of the alpha 1 (I) collagen gene.Semantic proximity Read ↗

An AP-1 Binding Sequence Is Essential for Regulation of the Human α2(I) Collagen (COL1A2) Promoter Activity by Transforming Growth Factor-βSemantic proximity Read ↗

Insulation of the ubiquitous Rxrb promoter from the cartilage-specific adjacent gene, Col11a2.Semantic proximity Read ↗

Cooperativity between far upstream enhancer and proximal promoter elements of the human {alpha}2(I) collagen (COL1A2) gene instructs tissue specificity in transgenic mice.Semantic proximity Read ↗

Regulation of type I collagen genes expressionSemantic proximity Read ↗

Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer.Semantic proximity Read ↗

Transcriptional regulation of the human α2(I) collagen gene (COL1A2), an informative model system to study fibrotic diseasesSemantic proximity Read ↗

Mice with a targeted intronic deletion in the Col1a1 gene respond to bleomycin-induced pulmonary fibrosis with increased expression of the mutant allele.Semantic proximity Read ↗

A methylation-responsive MDBP/RFX site is in the first exon of the collagen alpha2(I) promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.