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Article

Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men.

Clinical endocrinology - 1 Feb 2009

Vanbillemont Griet, Bogaert Veerle, De Bacquer Dirk, Lapauw Bruno, Goemaere Stefan, Toye Kaatje, Van Steen Kristel, Taes Youri, Kaufman Jean-Marc

Abstract excerpt

OBJECTIVE: In men there is a large interindividual variation of SHBG levels and consequently of testosterone (T) and E(2) levels. Family and twin studies suggested a strong genetic contribution, besides metabolic and hormonal influences. The aim of this study was to examine the influence of a missense mutation in exon 8 (Asp327Asn) and a (TAAAA)(n)-repeat in the promoter region of the SHBG gene, on SHBG and sex...

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Source

Identifiers

PMID: 18681858
DOI: 10.1111/j.1365-2265.2008.03365.x

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men.PMID 18681858Read ↗

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