Article
Association of SHBG gene polymorphism with menarche.
Molecular human reproduction - 1 Jun 2005
Xita N, Tsatsoulis A, Stavrou I, Georgiou I
Abstract excerpt
The age of menarche may be subject to hereditary influences but the specific determinants are unknown. Our aim was to investigate the possible association of a functional (TAAAA)n polymorphism in the promoter of the sex hormone-binding globulin (SHBG) gene with the timing of menarche. This polymorphism has been associated with polycystic ovary syndrome (PCOS) and is considered to contribute to SHBG levels. We...
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