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Article

COLIA1 Sp1 polymorphism predicts response of femoral neck bone density to cyclical etidronate therapy.

Calcified tissue international - 1 Mar 2002

Qureshi A M, Herd R J, Blake G M, Fogelman I, Ralston S H

Abstract excerpt

Genetic factors are important in the pathogenesis of osteoporosis but less is known about their possible role in predicting response to anti-osteoporotic therapy. Previous studies have shown that a polymorphic Sp1 binding site in the collagen type 1 alpha 1 gene (COLIA1) is associated with bone mineral density (BMD) and osteoporotic vertebral fracture. In this study we sought to determine if the COLIA1 Sp1...

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Identifiers

PMID: 11907712
DOI: 10.1007/s00223-001-1035-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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COLIA1 Sp1 polymorphism predicts response of femoral neck bone density to cyclical etidronate therapy.PMID 11907712Read ↗

Prediction of osteoporotic fractures by bone densitometry and COLIA1 genotyping: a prospective, population-based study in men and women.Semantic proximity Read ↗

Relation of alleles of the collagen type Ialpha1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women.Semantic proximity Read ↗

An Sp1 Binding Site Polymorphism in the COLIA1 Gene Predicts Osteoporotic Fractures in Both Men and WomenSemantic proximity Read ↗

COL1A1 Sp1 polymorphism predicts perimenopausal and early postmenopausal spinal bone loss.Semantic proximity Read ↗

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study.Semantic proximity Read ↗

Association between COLIA1 Sp1 alleles and femoral neck geometry.Semantic proximity Read ↗

Association of collagen type 1 alpha1 gene polymorphism with bone density in early childhood.Semantic proximity Read ↗

Collagen Ialpha1 Sp1 polymorphism, bone mass, and bone turnover in healthy French premenopausal women: the OFELY study.Semantic proximity Read ↗

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Association of the collagen type 1 (COL1A 1) Sp1 binding site polymorphism to femoral neck bone mineral density and wrist fracture in 1044 elderly Swedish women.Semantic proximity Read ↗

Haplotypes of promoter and intron 1 polymorphisms in the COLIA1 gene are associated with increased risk of osteoporosis.Semantic proximity Read ↗

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