Article
COLIA1 Sp1 polymorphism predicts response of femoral neck bone density to cyclical etidronate therapy.
Calcified tissue international - 1 Mar 2002
Qureshi A M, Herd R J, Blake G M, Fogelman I, Ralston S H
Abstract excerpt
Genetic factors are important in the pathogenesis of osteoporosis but less is known about their possible role in predicting response to anti-osteoporotic therapy. Previous studies have shown that a polymorphic Sp1 binding site in the collagen type 1 alpha 1 gene (COLIA1) is associated with bone m...
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