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Article

Collagen Ialpha1 polymorphism is associated with bone characteristics in Caucasian children and young adults.

Calcified tissue international - 1 Nov 2002

van der Sluis I M, de Muinck Keizer-Schrama S M P F, Pols H A P, Lequin M H, Krenning E P, Uitterlinden A G

Abstract excerpt

A large proportion of the variation in bone mass can be explained by genetic factors. We analyzed the G to T substitution in the Sp1 binding site in the first intron of the collagen type Ialpha1 (COLIA1) gene in relation to bone mass. The genotypes GG, GT, and TT were determined in 148 Caucasian children and young adults. We performed dual energy X-ray absorptiometry twice (mean follow-up time 4.4 years), and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12232678
DOI: 10.1007/s00223-001-2093-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Collagen Ialpha1 polymorphism is associated with bone characteristics in Caucasian children and young adults.PMID 12232678Read ↗

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