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Article

Therapeutic targets for polycystic kidney disease.

Expert opinion on therapeutic targets - 1 Jan 2016

Wilson Patricia D

Abstract excerpt

INTRODUCTION: Polycystic kidney disease (PKD) is a common genetic disease in which renal enlargement and loss of function is caused by progressive expansion of tubular cysts. To reverse the detrimental effects of PKD gene mutation(s) and to slow cystic expansion, new drug therapies are required. AREAS COVERED: The underlying cell biology leading to identification of molecular targets for PKD is reviewed. Specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26328773
DOI: 10.1517/14728222.2015.1083979

Genes

AVPR2
EGFR

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