Article
Validation of a targeted next-generation sequencing panel for pancreatic ductal adenocarcinomas.
Experimental and molecular pathology - 1 Oct 2024
Racu Marie-Lucie, Schiavo Andrea Alex, Van Campenhout Claude, De Nève Nancy, Masuy Thomas, Maris Calliope, Decaestecker Christine, Remmelink Myriam, Salmon Isabelle, D'Haene Nicky
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is reported to be amongst the cancers with the lowest survival rate at 5 years. In the present study we aimed to validate a targeted next-generation sequencing (tNGS) panel to use in clinical routine, investigating genes important for PDAC diagnostic, prognostic and potential theragnostic aspect. In this NGS panel we also designed target regions to inquire about loss of...
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