Article
Immunohistochemical study on the distribution of glycogen synthase kinase 3alpha in the central nervous system of SOD1(G93A) transgenic mice.
Neurological research - 1 Nov 2008
Chung Yoon Hee, Joo Kyeung Min, Kim Dae Jin, Kim Sung Su, Kim Kyung Yong, Lee Won Bok, Cha Choong Ik
Abstract excerpt
OBJECTIVE: To identify glycogen synthase kinase (GSK) 3alpha expression in a mouse model of familial amyotrophic lateral sclerosis (ALS), we investigated the changes of GSK3alpha in the central nervous system of SOD1(G93A) transgenic mice by immunohistochemistry. METHODS: We used 12 SOD1(G93A) transgenic and ten wild-type (wt) SOD1 transgenic mice bred by 'The Jackson Laboratory' under the strain designations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
