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Article

Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells.

Neuroscience letters - 8 Sept 1995

Sperber B R, Leight S, Goedert M, Lee V M

Abstract excerpt

Hyperphosphorylated tau protein is the major constituent of the paired helical filament (PHF), the major fibrous component of the neurofibrillary lesions of Alzheimer's disease (AD). Hyperphosphorylation of tau is believed to be the critical event that leads to filament assembly. Identification o...

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PMID: 8552282
DOI: 10.1016/0304-3940(95)11902-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8552282-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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