Article
Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3beta transgenes.
Neuroreport - 20 Oct 1997
Brownlees J, Irving N G, Brion J P, Gibb B J, Wagner U, Woodgett J, Miller C C
Abstract excerpt
In order to investigate the effect on tau of manipulating glycogen synthase kinase (GSK)-3beta activity in the brain, we created transgenic mice harbouring wild-type GSK-3beta genes or a mutant GSK-3beta that is predicted to be more active. Transgene-derived mRNAs were detected in the brains of a...
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