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Article

Efficient genetic method for establishing Drosophila cell lines unlocks the potential to create lines of specific genotypes.

PLoS genetics - 1 Aug 2008

Simcox Amanda, Mitra Sayan, Truesdell Sharon, Paul Litty, Chen Ting, Butchar Jonathan P, Justiniano Steven

Abstract excerpt

Analysis of cells in culture has made substantial contributions to biological research. The versatility and scale of in vitro manipulation and new applications such as high-throughput gene silencing screens ensure the continued importance of cell-culture studies. In comparison to mammalian systems, Drosophila cell culture is underdeveloped, primarily because there is no general genetic method for deriving new...

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Identifiers

PMID: 18670627
DOI: 10.1371/journal.pgen.1000142
PMCID: PMC2474701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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