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Article

Induction of epithelial tumors in Drosophila melanogaster heterozygous for the tumor suppressor gene wts.

Environmental and molecular mutagenesis - 1 Jan 2002

Eeken Jan C J, Klink Ilse, van Veen Bert L, Pastink Albert, Ferro Wouter

Abstract excerpt

The imaginal disk cells of Drosophila have a cell cycle that is very similar to that of mammalian cells. Data concerning factors inducing tumors in these cells may directly relate to the risk of these factors for inducing cancer in humans. One of the genes involved in the regulation of cell cycle control is wts (warts), the Drosophila homolog of the mammalian tumor suppressor gene LATS1. The Drosophila wts...

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Source

Identifiers

PMID: 12489118
DOI: 10.1002/em.10119

Genes

LATS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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