Article
Drosophila embryonic 'fibroblasts': extending mutant analysis in vitro.
Fly - 1 Jan 2000
Simcox Amanda A, Austin Christina L, Jacobsen Thomas L, Jafar-Nejad Hamed
Abstract excerpt
The in vivo analysis of Drosophila using genetics, with almost a hundred year history, has produced an immense body of knowledge about biology. In vitro analysis, while arguably the poor cousin to its in vivo relative, has a utility--in biochemical analyses and in cell-based screening, for example, with RNAi. A major block to the development of in vitro analysis has been the lack of an efficient genetic method to...
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