Article
Genes affecting cell competition in Drosophila.
Genetics - 1 Feb 2007
Tyler David M, Li Wei, Zhuo Ning, Pellock Brett, Baker Nicholas E
Abstract excerpt
Cell competition is a homeostatic mechanism that regulates the size attained by growing tissues. We performed an unbiased genetic screen for mutations that permit the survival of cells being competed due to haplo-insufficiency for RpL36. Mutations that protect RpL36 heterozygous clones include the tumor suppressors expanded, hippo, salvador, mats, and warts, which are members of the Warts pathway, the tumor...
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