Article
Genetic analysis implicates resistin in HIV lipodystrophy.
AIDS (London, England) - 20 Aug 2008
Ranade Koustubh, Geese William J, Noor Mustafa, Flint Oliver, Tebas Pablo, Mulligan Kathleen, Powderly William, Grinspoon Steven K, Dube Michael P
Abstract excerpt
OBJECTIVES: To investigate the role of genetic variation in influencing the risk of metabolic complications associated with highly active antiretroviral therapy (HAART). METHODS: Cluster analysis of metabolic traits of 189 patients enrolled in ACTG5005s, the metabolic substudy of ACTG384, a clinical trial of HAART, was performed to identify a subgroup of individuals with increased risk of developing a cluster of...
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