Article
Contribution of genetic background and antiretroviral therapy to body fat changes in antiretroviral-naive HIV-infected adults.
The Journal of antimicrobial chemotherapy - 1 Nov 2014
Egaña-Gorroño L, Martínez E, Pérez I, Escribà T, Domingo P, Gatell J M, Arnedo M
Abstract excerpt
OBJECTIVES: To evaluate the association of host genetics with changes in limb or trunk fat in a group of antiretroviral therapy (ART)-naive HIV-infected patients prospectively followed up according to the initiation and the type of ART. METHODS: Fifty single nucleotide polymorphisms (SNPs) in 26 genes, associated with obesity, insulin resistance, lipid metabolism or lipodystrophy in previously published genetic...
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