Article
Analysis of base excision and nucleotide excision repair in Candida albicans.
Microbiology (Reading, England) - 1 Aug 2008
Legrand Melanie, Chan Christine L, Jauert Peter A, Kirkpatrick David T
Abstract excerpt
Candida albicans, clinically the most important human fungal pathogen, rapidly develops resistance to antifungal drugs. The acquisition of resistance has been linked to various types of genome changes. As part of an ongoing study of this problem, we investigated mutation, genome stability and drug resistance acquisition in C. albicans strains with deletions in the base excision repair (BER) genes NTG1, APN1 and...
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