Article
A comprehensive model of mutations affecting fitness and inferences for Arabidopsis thaliana.
Evolution; international journal of organic evolution - 1 Mar 2002
Shaw Frank H, Geyer Charles J, Shaw Ruth G
Abstract excerpt
As the ultimate source of genetic variation, spontaneous mutation is essential to evolutionary change. Theoretical studies over several decades have revealed the dependence of evolutionary consequences of mutation on specific mutational properties, including genomic mutation rates, U, and the effects of newly arising mutations on individual fitness, s. The recent resurgence of empirical effort to infer these...
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