Article
Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease.
Journal of gastroenterology and hepatology - 1 Sept 2008
Andoh Akira, Tsujikawa Tomoyuki, Ban Hiromitsu, Hashimoto Takayoshi, Bamba Shigeki, Ogawa Atsuhiro, Sasaki Masaya, Saito Yasuharu, Fujiyama Yoshihide
Abstract excerpt
BACKGROUND AND AIM: There have been no reports on 6-thioguanine nucleotide (6-TGN) concentrations in Japanese patients with inflammatory bowel disease (IBD) undergoing azathioprine (AZA) or 6-mercaptopurine (6-MP) therapy. The aim of this study was to assess 6-TGN concentrations in Japanese IBD patients. METHODS: Eighty-three patients with Crohn's disease (n = 42) and ulcerative colitis (n = 41) were enrolled. In...
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