Article
Monitoring thiopurine metabolites in korean pediatric patients with inflammatory bowel disease.
Yonsei medical journal - 1 Sept 2014
Kim Mi Jin, Lee Soo Youn, Choe Yon Ho
Abstract excerpt
PURPOSE: This study aimed to assess the role of thiopurine S-methyltransferase (TPMT) and 6-thioguanine nucleotide (6-TGN) as predictors of clinical response and side effects to azathioprine (AZA), and estimate the optimal AZA dose in Korean pediatric inflammatory bowel disease (IBD) patients. MATERIALS AND METHODS: One hundred and nine pediatric IBD patients in whom AZA treatment was required were enrolled....
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