Article
A prospective, open-label trial of 6-thioguanine in patients with ulcerative or indeterminate colitis.
Scandinavian journal of gastroenterology - 1 Oct 2005
Teml Alexander, Schwab Matthias, Harrer Marieluise, Miehsler Wolfgang, Schaeffeler Elke, Dejaco Clemens, Mantl Martina, Schneider Barbara, Vogelsang Harald, Reinisch Walter
Abstract excerpt
OBJECTIVE: 6-thioguanine (6-TG) has emerged as a promising therapeutic alternative in patients with Crohn's disease intolerant or resistant to azathioprine (AZA) and/or 6-mercaptopurine (6-MP). The aim of the present study was to evaluate the safety and efficacy of 6-TG in patients with ulcerative colitis (UC) or indeterminate colitis (IC) intolerant or resistant to AZA/6-MP. MATERIAL AND METHODS: Twenty patients...
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