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Article

Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis.

Journal of gastroenterology - 1 Jan 2003

Hibi Toshifumi, Naganuma Makoto, Kitahora Tetsuji, Kinjyo Fukunori, Shimoyama Takashi

Abstract excerpt

BACKGROUND: 6-Mercaptopurine (6-MP) and azathioprine (AZA) have been used in patients with Crohn's disease (CD) and ulcerative colitis (UC) for reducing the dose of steroids and maintaining remission. However, some patients treated with 6-MP/AZA develop bone marrow suppression, one of the most serious side effects. The aim of this study was to evaluate the efficacy and safety of low-dose AZA (0.6-1.2 mg/kg per...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dose-Response Relationship, Drug

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Source

Identifiers

PMID: 14505127
DOI: 10.1007/s00535-003-1139-2

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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