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Article

Relationship between azathioprine dosage, 6-thioguanine nucleotide levels, and therapeutic response in pediatric patients with IBD treated with azathioprine.

Inflammatory bowel diseases - 1 May 2015

Lee Mi-Na, Kang Ben, Choi So Yoon, Kim Mi Jin, Woo Sook Young, Kim Jong-Won, Choe Yon Ho, Lee Soo-Youn

Abstract excerpt

BACKGROUND: Azathioprine (AZA) is commonly used to treat IBD either alone or in combination with mesalazine. However, there are relatively few studies concerning the relationship between AZA dose, thiopurine metabolite levels, and therapeutic response in pediatric patients treated with both AZA and mesalazine. METHODS: We retrospectively investigated the relationship between AZA dose, thiopurine metabolite...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25851563
DOI: 10.1097/MIB.0000000000000347

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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