A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis.

doi:10.1093/carcin/bgn172

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis.

Carcinogenesis - 1 Oct 2008

Shen Jie, Ambrosone Christine B, DiCioccio Richard A, Odunsi Kunle, Lele Shashikant B, Zhao Hua

Abstract excerpt

A G to C polymorphism (rs2910164) is located within the sequence of miR-146a precursor, which leads to a change from a G:U pair to a C:U mismatch in its stem region. The predicted miR-146a target genes include BRCA1 and BRCA2, which are key breast and ovarian cancer genes. To examine whether rs29...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset

Share to Breast Neoplasms

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to MicroRNAs

Share to Ovarian Neoplasms

Share to Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 18660546
DOI: 10.1093/carcin/bgn172

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18660546-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis.PMID 18660546Read ↗

Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients.Semantic proximity Read ↗

Functional SNP in stem of mir-146a affects Her2 status and breast cancer survival.Semantic proximity Read ↗

A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma.Semantic proximity Read ↗

Associations of Single Nucleotide Polymorphism in miR-146a Gene with Susceptibility to Breast Cancer in the Iranian Female.Semantic proximity Read ↗

The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis.Semantic proximity Read ↗

The rs2910164:G>C SNP in the MIR146A gene is not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

A functional polymorphism in Pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population.Semantic proximity Read ↗

A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo.Semantic proximity Read ↗

Association between a Genetic Variant in the hsa-miR-146a Gene and Cancer Risk: An Updated Meta-Analysis.Semantic proximity Read ↗

Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases.Semantic proximity Read ↗

Mutation screening of MIR146A/B and BRCA1/2 3'-UTRs in the GENESIS study.Semantic proximity Read ↗

Association Between miR-146a rs2910164 Polymorphism and Breast Cancer Susceptibility: An Updated Meta-Analysis of 9545 Cases and 10030 Controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.